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Treating ‘osteoporosis’: a near miss in an unusual case of FGF-23-mediated hypophosphataemic osteomalacia

Mike Lin Department of Endocrinology, Concord Repatriation General Hospital, Concord NSW, Australia

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Kirtan Ganda Department of Endocrinology, Concord Repatriation General Hospital, Concord NSW, Australia
The University of Sydney Concord Clinical School, Concord NSW, Australia.

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improvement in bone density. Bone density T score ( s.d. ) Change from previous L1–L4  March 2021 0.86 g/cm 2 –2.8  March 2022 0.89 g/cm 2 –2.7 +2.7% Left femoral neck  March 2021 0.77 g/cm 2 –1

Taxonomy:
Clinical Overview, Gland/Organ, Bone, Topic, Bone, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, Asian - other, Country of Treatment, Australia, Publication Details, Case Report Type, Insight into disease pathogenesis or mechanism of therapy
DOI:
https://doi.org/10.1530/EDM-22-0300
Volume/Issue:
Volume 2022: Issue 1
Open access

A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction

Rikako Nakajima Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Motohiro Sekiya Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Yasuhisa Furuta Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Takafumi Miyamoto Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Masashi Sato Department of Gastroenterology, Faculty of Medicine, University of Tsukuba

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Kuniaki Fukuda Department of Gastroenterology, Faculty of Medicine, University of Tsukuba
Department of Gastroenterology, Kasumigaura Medical Center, 2-7-14 Shimotakatsu, Tsuchiura, Ibaraki, Japan

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Keiichiro Hattori Department of Hematology, Faculty of Medicine, University of Tsukuba

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Yasuhito Suehara Department of Hematology, Faculty of Medicine, University of Tsukuba

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Mamiko Sakata-Yanagimoto Department of Hematology, Faculty of Medicine, University of Tsukuba

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Shigeru Chiba Department of Hematology, Faculty of Medicine, University of Tsukuba

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Yuka Okajima Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Takashi Matsuzaka Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan
Transborder Medical Research Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Satoru Takase Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, the University of Tokyo, Bunkyo, Tokyo, Japan

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Mikio Takanashi Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, the University of Tokyo, Bunkyo, Tokyo, Japan

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Hiroaki Okazaki Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, the University of Tokyo, Bunkyo, Tokyo, Japan

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Yusuke Takashima Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Mikiko Yuhara Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Yuta Mitani Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Nako Matsumoto Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Yuki Murayama Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Mariko Ohyama Osawa Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Nami Ohuchi Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Daichi Yamazaki Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Sayuri Mori Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Yoko Sugano Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Yoshinori Osaki Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Hitoshi Iwasaki Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Hiroaki Suzuki Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Hitoshi Shimano Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

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Shimura T Istiqamah N Han SI Mizunoe Y Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice . Biochimica et Biophysica Acta. Molecular Basis of Disease 2022 1868 166339

Taxonomy:
Clinical Overview, Gland/Organ, Liver, Topic, Diabetes, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, Asian - Japanese, Country of Treatment, Japan, Publication Details, Case Report Type, Insight into disease pathogenesis or mechanism of therapy
DOI:
https://doi.org/10.1530/EDM-22-0368
Volume/Issue:
Volume 2022: Issue 1
Open access

Subacute thyroiditis post viral vector vaccine for COVID-19

Caoimhe Casey University Hospital Kerry, Tralee, Co. Kerry, Ireland

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Tom Higgins University Hospital Kerry, Tralee, Co. Kerry, Ireland

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.26.47.2101021 ) 7 World Health Organisation . WHO Coronavirus (COVID-19) Dashboard . W HO , 2022 . (available at: Covid19.who.int) 34693241 8 Siolos A Gartzonika K Tigas S . Thyroiditis following vaccination against COVID-19: report of two cases and

Taxonomy:
Clinical Overview, Gland/Organ, Thyroid, Topic, Thyroid, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, White, Country of Treatment, Ireland, Related Disciplines, General practice, Publication Details, Case Report Type, Unusual effects of medical treatment
DOI:
https://doi.org/10.1530/EDM-21-0193
Volume/Issue:
Volume 2022: Issue 1
Open access

Metastatic mixed VIPoma/PPoma-induced diarrhoea causing renal failure

George Brown Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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Anthony Mark Monaghan Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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Richard Fristedt Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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Emma Ramsey Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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Ma’en Al-Mrayat Department of Endocrinology, University Hospital Southampton, Southampton, UK

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Rushda Rajak Department of Cellular Pathology, University Hospital Southampton, Southampton, UK

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Thomas Armstrong Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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Arjun Takhar Department of Hepatobiliary & Pancreatic Surgery, University Hospital Southampton, Southampton, UK

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panels B and C indicate liver metastases. He will remain on lanreotide injections for a further 6 months before repeat Ga68 PET/CT and MRI imaging. If his disease remains stable, the plan at the time as of February 2022 was to proceed to

Taxonomy:
Clinical Overview, Gland/Organ, Pancreas, Topic, Endocrine-related cancer, Patient Demographics, Age, Adult, Gender, Male, Ethnicity, White, Country of Treatment, Ireland, Related Disciplines, Surgery, Publication Details, Case Report Type, Unique/unexpected symptoms or presentations of a disease
DOI:
https://doi.org/10.1530/EDM-22-0231
Volume/Issue:
Volume 2022: Issue 1
Open access

Severe type 2 diabetes (T2D) remission using a very low-calorie ketogenic diet (VLCKD)

Livia Lugarinho Correa Department of Obesity, Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione (IEDE), Rio de Janeiro, Brazil

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Priscila Alves Medeiros de Sousa Department of Obesity, Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione (IEDE), Rio de Janeiro, Brazil

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Leticia Dinis Department of Obesity, Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione (IEDE), Rio de Janeiro, Brazil

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Luana Barboza Carloto Department of Obesity, Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione (IEDE), Rio de Janeiro, Brazil

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Maitane Nuñez-Garcia Pronokal® Group, Barcelona, Spain

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Ignacio Sajoux Pronokal® Group, Barcelona, Spain

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Sidney Senhorini Betaclínica-Centro de Diabetes de Maringá, Paraná, Brazil

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Background The International Diabetes Federation estimates that 1 in 10 people aged 20–79 years have diabetes, which equates to 537 million people in the world. By 2045, this number will increase to 784 million (idf.org in 2022). There is a

Taxonomy:
Clinical Overview, Gland/Organ, Adipose tissue, Topic, Diabetes, Obesity, Patient Demographics, Age, Adult, Gender, Male, Ethnicity, Hispanic or Latino - Central American or South American, Country of Treatment, Brazil, Publication Details, Case Report Type, Insight into disease pathogenesis or mechanism of therapy
DOI:
https://doi.org/10.1530/EDM-22-0295
Volume/Issue:
Volume 2022: Issue 1
Open access

Hiccups as the first presentation of secondary adrenal insufficiency associated with advanced cervical cancer

Toshitaka Sawamura Department of Internal Medicine, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan
Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan

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Shigehiro Karashima Department of Health Promotion and Medicine of the Future, Kanazawa University, Kanazawa, Ishikawa, Japan

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Ai Ohmori Department of Internal Medicine, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan
Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan

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Kei Sawada Department of Internal Medicine, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan

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Daisuke Aono Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
Department of Health Promotion and Medicine of the Future, Kanazawa University, Kanazawa, Ishikawa, Japan

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Mitsuhiro Kometani Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
Department of Health Promotion and Medicine of the Future, Kanazawa University, Kanazawa, Ishikawa, Japan

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Yoshiyu Takeda Department of Internal Medicine, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan

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Takashi Yoneda Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
Department of Health Promotion and Medicine of the Future, Kanazawa University, Kanazawa, Ishikawa, Japan

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and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: a prospective, observational, cross-sectional human and two translational mouse studies . EBiomedicine 2022 80 104057. ( https

Taxonomy:
Clinical Overview, Gland/Organ, Adrenal, Topic, Adrenal, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, Asian - Japanese, Country of Treatment, Japan, Publication Details, Case Report Type, Unique/unexpected symptoms or presentations of a disease
DOI:
https://doi.org/10.1530/EDM-22-0286
Volume/Issue:
Volume 2022: Issue 1
Open access

Adult-onset Langerhans cell histiocytosis changing CNS lesion from pituitary to suprasellar extension

Yuji Kadowaki Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Mitsuru Nishiyama Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan
Health Care Center, Kochi University, Kochi City, Kochi, Japan

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Makoto Nakamura Department of Hematology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Hiroyuki Morisaka Department of Dermatology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Shimpei Fujimoto Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Yoshio Terada Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Kensuke Kojima Department of Hematology, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan

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Ichihara A Kawamata T . Clinical features and difficulty in diagnosis of Langerhans cell histiocytosis in the hypothalamic-pituitary lesion . Endocrine Journal 2022 69 441 – 449 . ( https://doi.org/10.1507/endocrj.EJ21-0341 ) 10.1507/endocrj.EJ21

Taxonomy:
Clinical Overview, Gland/Organ, Pituitary, Topic, Pituitary, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, Asian - Japanese, Country of Treatment, Japan, Related Disciplines, Neurology, Publication Details, Case Report Type, Unique/unexpected symptoms or presentations of a disease
DOI:
https://doi.org/10.1530/EDM-22-0232
Volume/Issue:
Volume 2022: Issue 1
Open access

Diabetes mellitus-induced lower urinary tract symptoms and hepatic steatosis in an older male

Nnennaya U Opara Emergency Medicine, Charleston Area Medical Centre, Institute for Academic Medicine, Charleston, West Virginia, USA

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& Opara EU. Applying the principles of Evidence-Based Public Health in addressing the diabetes mellitus epidemic among African-American communities living in the district of Colombia: A literature review . Journal of Public Health Research 2022 11

Taxonomy:
Clinical Overview, Gland/Organ, Liver, Topic, Diabetes, Patient Demographics, Age, Geriatric, Gender, Male, Ethnicity, Black - African, Country of Treatment, United States, Related Disciplines, Geriatrics, Publication Details, Case Report Type, Insight into disease pathogenesis or mechanism of therapy
DOI:
https://doi.org/10.1530/EDM-22-0290
Volume/Issue:
Volume 2022: Issue 1
Open access

Hypertriglyceridemia as a main feature associated with 17q12 deletion syndrome-related hepatocyte nuclear factor 1β-maturity-onset diabetes of the young

Yotsapon Thewjitcharoen Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand

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Soontaree Nakasatien Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand

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Tsz Fung Tsoi Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China

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Cadmon K P Lim Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China

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Thep Himathongkam Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand

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Juliana C N Chan Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
Asia Diabetes Foundation, Shatin, Hong Kong SAR, China

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A Patel K . Syndromic monogenic diabetes genes should be tested in patients with a clinical suspicion of maturity-onset diabetes of the young . Diabetes 2022 71 530 – 537 . ( https://doi.org/10.2337/db21-0517 ) 10.2337/db21-0517 9 Dron JS

Taxonomy:
Clinical Overview, Gland/Organ, Pancreas, Topic, Diabetes, Patient Demographics, Age, Adult, Gender, Female, Ethnicity, Asian - other, Country of Treatment, Thailand, Related Disciplines, Genetics, Publication Details, Case Report Type, Unique/unexpected symptoms or presentations of a disease
DOI:
https://doi.org/10.1530/EDM-22-0297
Volume/Issue:
Volume 2022: Issue 1
Open access

45,X male – rare case of unbalanced translocation of Y chromosome to chromosome 2 presenting with developmental delay, learning difficulty and obesity

Jananie Suntharesan Department of Endocrinology, Alder Hey Children’s Hospital, Eaton Road, Liverpool, UK

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Louise Apperley Department of Endocrinology, Alder Hey Children’s Hospital, Eaton Road, Liverpool, UK

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Senthil Senniappan Department of Endocrinology, Alder Hey Children’s Hospital, Eaton Road, Liverpool, UK

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behavioral alterations in mice . Molecular Autism 2022 13 19. ( https://doi.org/10.1186/s13229-022-00497-3 ) 24 Bottini N MacMurray J Peters W Rostamkhani M Comings DE . Association of the acid phosphatase (ACP1) gene with triglyceride levels

Taxonomy:
Clinical Overview, Gland/Organ, Testes, Topic, Genetics and mutation, Paediatric endocrinology, Patient Demographics, Age, Adolescent/young adult, Gender, Female, Ethnicity, Asian - other, Country of Treatment, United Kingdom, Publication Details, Case Report Type, New disease or syndrome: presentations/diagnosis/management
DOI:
https://doi.org/10.1530/EDM-22-0320
Volume/Issue:
Volume 2022: Issue 1
Open access