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Reiner Jumpertz von Schwartzenberg, Ulf Elbelt, Manfred Ventz, Knut Mai, Tina Kienitz, Lukas Maurer, Thomas Rose, Jens C Rückert, Christian J Strasburger, and Joachim Spranger

recommended treatment approach. In some cases reduction of tumor mass may also include radiotherapy, cryoablation, or embolization. In advanced stages of the disease, reduction of tumor mass may no longer be a feasible treatment option, and in these palliative

Open access

Arshpreet Kaur and Stephen J Winters

ingested 8–10 Tums daily for heartburn for 1 week, followed by poor appetite and lethargy. Past medical records revealed normocalcemia and normal renal function. Investigation He had severe hypercalcemia of 17.4 mg/dl (reference range 8.9–10.3), a

Open access

Katia Regina Marchetti, Maria Adelaide Albergaria Pereira, Arnaldo Lichtenstein, and Edison Ferreira Paiva

months prior to the described events with bloating, weakness, lack of appetite, nausea, weight loss, dyspnea and edema of the lower limbs. In the preceding 3 months, her general condition had worsened, and she experienced episodes of mental confusion and

Open access

Benjamin G Challis, Nicolai J Wewer Albrechtsen, Vishakha Bansiya, Keith Burling, Peter Barker, Bolette Hartmann, Fiona Gribble, Stephen O'Rahilly, Jens J Holst, and Helen L Simpson

Background Pancreatic neuroendocrine tumours (pNETs) that secrete glucagon are associated with well-recognised clinical features of the glucagonoma syndrome including necrolytic migratory erythema (NME), weight loss, diarrhoea, anaemia

Open access

Andrea Pucci, Wui Hang Cheung, Jenny Jones, Sean Manning, Helen Kingett, Marco Adamo, Mohamed Elkalaawy, Andrew Jenkinson, Nicholas Finer, Jacqueline Doyle, Majid Hashemi, and Rachel L Batterham

 kg/m 2 ). Her initial post-operative course was unremarkable, except she reported marked loss of appetite. One-year post-SG, she reported continued anorexia, her weight had decreased to 64.6 kg, and her BMI had decreased to 22 kg/m 2 ; this

Open access

Anna Tortora, Domenico La Sala, and Mario Vitale

dosage (1.2 μg/kg/day) and invited the patient to a short interval follow-up of about 2 months. Two months later, the woman reported to us the onset of gastrointestinal symptoms, initiated 3 weeks before, including nausea, weight loss, flatulence

Open access

Kah-Yin Loke, Andrew Sng Anjian, Yvonne Lim Yijuan, Cindy Ho Wei Li, Maria Güemes, and Khalid Hussain

. She was subsequently followed up at the paediatric endocrine specialist clinic. She experienced no hypoglycaemic episodes and was weaned off glucose polymers and cornstarch with a gradual reduction of diazoxide to a minimum dose of 9 mg/kg/day at 4

Open access

Anthony Logaraj, Venessa H M Tsang, Shahrir Kabir, and Julian C Y Ip

, catecholamine-related increased adrenal blood flow and adrenal vein spasm. Case presentation A 93-year-old female presented with two weeks of left upper quadrant abdominal pain associated with 10 kg unintentional weight loss. Pre-operative computed

Open access

V Larouche and M Tamilia

immunosuppressant, presented to the emergency room of our hospital with a two-week history of daily fevers up to 39°C, a sore throat, occasional palpitations and diaphoresis, decreased appetite and an unintentional 10 kg weight loss over the same time course. She

Open access

A Chinoy, N B Wright, M Bone, and R Padidela

. Case presentation A nine-year-old girl, who had been previously fit and well, presented to the children’s emergency department with a 3-week history of persistent and recurrent vomiting, abdominal pain, poor oral intake and weight loss. DKA was