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Christopher Muir, Anthony Dodds and Katherine Samaras

patients. Complaints of bone and/or joint pain should prompt screening with targeted magnetic resonance imaging. It remains unclear whether DBA predisposes to bone loss in its own right, but irrespective, osteoporosis screening with bone mineral

Open access

Eleanor P Thong, Sarah Catford, Julie Fletcher, Phillip Wong, Peter J Fuller, Helena Teede and Frances Milat

bone disease. Although T1DM is an established risk factor for osteoporosis and fracture, bone health in patients with T1DM is not routinely assessed. This may be in part due to the lack of guidelines for fracture risk assessment and management of such

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Hans-Christof Schober, Christian Kneitz, Franziska Fieber, Kathrin Hesse and Henry Schroeder

abnormal production of FGF-23, and phosphate is eliminated to a greater extent ( 1 ). Phosphate and calcium are linked to each other in blood as a calcium–phosphate product. The reduction of serum phosphate levels impairs the calcification of bone, and

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Alessandro Mantovani, Maddalena Trombetta, Chiara Imbriaco, Riccardo Rigolon, Lucia Mingolla, Federica Zamboni, Francesca Dal Molin, Dario Cioccoloni, Viola Sanga, Massimiliano Bruti, Enrico Brocco, Michela Conti, Giorgio Ravenna, Fabrizia Perrone, Vincenzo Stoico and Enzo Bonora

following days, coinciding with the worsening of fever, systemic symptoms, and back pain, CRP (334mg/L) and WBC (17×10 9 /L) significantly increased. Foot bone biopsy and two sets of blood cultures indicated Staphylococcus aureus infection. The

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M L Gild, L Heath, J Y Paik, R J Clifton-Bligh and B G Robinson

differentiated thyroid cancer guidelines. The most common presentation of MSO involves pelvic mass symptoms such as ascites or pain ( 4 ). The case described is a unique presentation of this rare disease. It highlights how bone metastases can be the initial

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Nobuhiro Miyamura, Shuhei Nishida, Mina Itasaka, Hirofumi Matsuda, Takeshi Ohtou, Yasuhiro Yamaguchi, Daisuke Inaba, Sadahiro Tamiya and Tetsuo Nakano

Background Hepatitis C-associated osteosclerosis (HCAO) is a very rare disorder in which an extremely rapid bone turnover occurs, resulting in generalized osteosclerosis. Affected patients suffer from excruciating deep bone pain in

Open access

Davi da Silva Barbirato, Mariana Fampa Fogacci, Mariana Arruda, Monique Oliveira Rodrigues and Leonardo Vieira Neto

Background Osteopetrosis (OP) comprehends a group of conditions, clinically and genetically heterogeneous, presenting on radiographs increased bone density, deriving from irregularities in osteoclast differentiation or function ( 1 ). In all

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Shintaro Kawai, Hiroyuki Ariyasu, Yasushi Furukawa, Reika Yamamoto, Shinsuke Uraki, Ken Takeshima, Kenji Warigaya, Yuji Nakamoto and Takashi Akamizu

-DOTATOC-PET/CT), systemic venous sampling (SVS) and 3T-magnetic resonance imaging (MRI). Case presentation A 53-year-old female was admitted to a hospital with bone pain in the limbs, rib cage and buttocks for half a year. Laboratory data showed elevated alkaline

Open access

Anna Luiza Galeazzi Rech, Yvon Stüve, Andreas Toepfer and Katrin E Schimke

, autonomic neuropathy, trauma and metabolic abnormalities of bone) results in an acute localized inflammatory condition leading to varying degrees and patterns of progressive bone destruction, subluxation, dislocation and deformity in the final, chronic state

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Hanna Remde, Elke Kaminsky, Mathias Werner and Marcus Quinkler

not have any bone problems, neither bone tumors nor deformities, but the patient's father was reported to have the same kind of bone affections. Thus, an additional genetic disease was made: HMO. In 2011, the patient suffered from increasing pain of