treatment is indicated, since there is no cure for MSD. In our case, we referred our patient to a dermatologist due to dermatologic symptoms (ichthyosis) to treat her by applying one of the many skin softeners available in the market. In our experience
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Nami Mohammadian Khonsari, Benyamin Hakak-Zargar, Tessa Voth, and Shahab Noorian
Salvatore Cannavò and Serafinella Patrizia Cannavò
, 43 patients showed self-induced dermatological lesions ( 2 ). They were generalized or localized especially into the breast, face, legs, or genitalia. These pathomimic lesions are generally characterized by constant picking of the skin, leading to
Ricaurte Crespo-Trevino, Jade Schiffman, Shoaib Ugradar, Kimberly Cockerham, Raymond Douglas, David de Leon-Garza, and Rosa Tang
438 – 446 . ( https://doi.org/10.1210/jcem.87.2.8220 ) 2 Fatourechi V Pretibial myxedema: pathophysiology and treatment options . American Journal of Clinical Dermatology 2005 6 295 – 309 . ( https://doi.org/10.2165/00128071-200506050-00003 ) 10
Matthew J Verheyden, Natassia Rodrigo, Anthony J Gill, and Sarah J Glastras
is currently stable ( Fig. 3 ). Diabetes remains well-controlled, with no evidence of macrovascular or microvascular disease. Dermatology Life Quality Index (DLQI) score is 10/30, indicating moderate effect on quality of life (QoL) mostly due to
Jenny S W Yun, Chris McCormack, Michelle Goh, and Cherie Chiang
-Candiani J González-González JG Gómez-Flores M . Skin manifestations of insulin resistance: from a biochemical stance to a clinical diagnosis and management . Dermatology and Therapy 2017 7 37 – 51 . ( https://doi.org/10.1007/s13555-016-0160-3 ) 10
Najoua Rbiai, Ikram Mahroug, Nada Zizi, and Hanane Latrech
. Calcinosis cutis occurring in association with autoimmune connective tissue disease: the Mayo Clinic experience with 78 patients, 1996–2009 . Archives of Dermatology 2012 148 455 – 462 . ( https://doi.org/10.1001/archdermatol.2011.2052 ) 10.1001/archdermatol
Melissa Katz, Simon Smith, Luke Conway, and Ashim Sinha
Summary
Diabetes mellitus is a well-recognised risk factor for melioidosis, the disease caused by Burkholderia pseudomallei, which is endemic in northern Australia and Southeast Asia. We present the initial diagnostic dilemma of a febrile patient from northern Australia with type 1 diabetes mellitus and negative blood cultures. After a 6-week history of fevers and undifferentiated abdominal pain, MRI of her spine revealed a psoas abscess. She underwent drainage of the abscess which cultured B. pseudomallei. She completed 6 weeks of intravenous (IV) ceftazidime and oral trimethoprim/sulphamethoxazole (TMP/SMX) followed by a 12-week course of oral TMP/SMX. We postulate that the likely route of infection was inoculation via her skin, the integrity of which was compromised from her insulin pump insertion sites and an underlying dermatological condition.
Learning points:
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Diabetes mellitus is the strongest risk factor for developing melioidosis.
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Atypical infections need to be considered in individuals with diabetes mellitus who are febrile, even if blood cultures are negative.
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There is heterogeneity in the clinical presentation of melioidosis due to variable organ involvement.
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Consider melioidosis in febrile patients who have travelled to northern Australia, Asia and other endemic areas.
Dimitrios Haidopoulos, George Bakolas, and Lina Michala
156 205 – 210 . ( doi:10.1111/j.1365-2249.2009.03895.x ) Smith YR & Haefner HK 2004 Vulvar lichen sclerosus: pathophysiology and treatment . American Journal of Clinical Dermatology 5 105 – 125 . ( doi:10
Silvia M Becerra-Bayona, Víctor Alfonso Solarte-David, Claudia L Sossa, Ligia C Mateus, Martha Villamil, Jorge Pereira, and Martha L Arango-Rodríguez
Cuende N Arias-Santiago S . Mesenchymal stromal cells: properties and role in management of cutaneous diseases . Journal of the European Academy of Dermatology and Venereology 2017 31 414 – 423 . ( https://doi.org/10.1111/jdv.13934 ) 4
Irene Berges-Raso, Olga Giménez-Palop, Elisabeth Gabau, Ismael Capel, Assumpta Caixàs, and Mercedes Rigla
intratesticular testosterone production and is thus directly harmful to fertility prospects. Case presentation A 32-year-old man with congenital ichthyosis managed in our hospital’s Dermatology Department was referred to our endocrinology department for
