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Alexandra Rose Pain, Josh Pomroy and Andrea Benjamin

Background Hamman’s syndrome (spontaneous subcutaneous emphysema and pneumomediastinum) is a rare complication of diabetic ketoacidosis (DKA). It is important to consider Boerhaave’s syndrome as a differential diagnosis, particularly in

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Miriam Hinaa Ahmad and Ismat Shafiq

with asparaginase in conjunction with glucocorticoids. The reported incidence is about 10–15% ( 2 ). Hyperglycemia is usually self-limiting and resolves after treatment but it may persist and deteriorate to diabetic ketoacidosis (DKA). DKA is rare with

Open access

Gordon Sloan, Tania Kakoudaki and Nishant Ranjan

pressure and cardiovascular outcomes have been reported with the drug class ( 2 ). Concerns were raised regarding the occurrence of diabetic ketoacidosis (DKA) in patients taking SGLT-2 inhibitors ( 3 ). The precise risk of DKA associated with prescription

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A Majid and B J Wheeler

Background Diabetic ketoacidosis (DKA) is an endocrine emergency occurring in patients with both new-onset and established type 1 diabetes (T1DM). In brief, the diagnosis is based on clinical suspicion followed by fulfillment of biochemical

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Shivani Patel, Venessa Chin and Jerry R Greenfield

and urothelial cancers. We report a case of fulminant diabetic ketoacidosis associated with durvalumab use in non-small-cell lung cancer followed by subsequent primary hypothyroidism. Case presentation A 49-year-old female presented to her

Open access

Cliona Small, Aoife M Egan, El Muntasir Elhadi, Michael W O’Reilly, Aine Cunningham and Francis M Finucane

Background The occurrence of hyperglycaemic ketosis and diabetic ketoacidosis (DKA) as manifestations of type 2 rather than type 1 diabetes has been well established for some time ( 1 , 2 ). However, awareness of this among clinicians is

Open access

Prashanth Rawla, Anantha R Vellipuram, Sathyajit S Bandaru and Jeffrey Pradeep Raj

Background Diabetic ketoacidosis (DKA) is defined as a clinical triad comprising metabolic acidosis, hyperglycemia and increased ketone bodies in the blood and urine. Hyperglycemia is usually the hallmark for the diagnosis of DKA ( 1

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Clarissa Ern Hui Fang, Mohammed Faraz Rafey, Aine Cunningham, Sean F Dinneen and Francis M Finucane

-generation antipsychotics had a 32% increased risk of developing diabetes, with the risk being 24% higher in those on risperidone ( 2 ). Diabetic ketoacidosis (DKA) is also more common in patients taking antipsychotic drugs ( 3 ). This tends to occur within 6 months of

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Senhong Lee, Aparna Morgan, Sonali Shah and Peter R Ebeling

Background The rapid development of diabetic ketoacidosis after a single dose of an immune checkpoint inhibitor is extremely rare. This case highlights the importance of glycemic surveillance in patients receiving immune checkpoint inhibitors

Open access

A Chinoy, N B Wright, M Bone and R Padidela

Background Children with type 1 diabetes mellitus often present in diabetic ketoacidosis (DKA). DKA causes varying degrees of derangement of fluid balance and electrolytes due to hyperglycaemia-induced osmotic fluid shifts, osmotic diuresis