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Viktoria F Koehler, Patrick Keller, Elisa Waldmann, Nathalie Schwenk, Carolin Kitzberger, Kathrin A Schmohl, Thomas Knösel, Christian Georg Stief, and Christine Spitzweg

hormones, however, in 8% of cases clinical and biochemical features of hyperthyroidism have been described ( 4 ). Around 40% of cases are asymptomatic and are accidentally discovered by routine ultrasound ( 5 ). In symptomatic cases of struma ovarii, common

Open access

Ray Wang, Benjamin Solomon, Stephen J Luen, Owen W.J. Prall, Christine Khoo, Anthony J Gill, Jeremy Lewin, and Nirupa Sachithanandan

heterogeneity, which can make accurate diagnosis difficult in some cases. Histologically, ACC typically immunostains for steroidogenic factor 1 (SF1), MelanA, alpha-inhibin, calretinin and synaptophysin, without staining for cytokeratins, S100 and chromogranin A

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Vishal Navani, James F Lynam, Steven Smith, Christine J O’Neill, and Christopher W Rowe

). A clinical diagnosis of metastatic prostate cancer was made, with the identified lesions ascribed to prostate cancer metastases, and he was commenced on ADT with leuprorelin (GnRH analogue) and cyproterone acetate (androgen receptor antagonist

Open access

Michail Katsamakas, Eleni Tzitzili, Maria Boudina, Anastasia Kiziridou, Rosalia Valeri, Georgios Zafeiriou, and Alexandra Chrisoulidou

in the second case. Apart from the difficult differential diagnosis between thyroid sarcoidosis and other thyroid diseases, its diagnosis remains elusive, when other causes of granulomatous inflammation are contemplated, such as tuberculosis, fungal

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Nobuyuki Nishi, Ken Takeshima, Shuhei Morita, Hiroshi Iwakura, Masahiro Nishi, and Takaaki Matsuoka

pancreas, lacrimal glands, salivary gland, thyroid, lungs, kidneys, and the retroperitoneum; the pituitary gland can also be affected ( 1 , 2 ). IgG4-related hypophysitis is commonly observed in elderly men and presents as a thickened pituitary stalk and

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Keita Tatsushima, Akira Takeshita, Shuji Fukata, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Hiroshi Nishioka, and Yasuhiro Takeuchi

-photon emission CT/CT, the area with strong signal shifted from the normal thyroid gland to the nodule, and the signal in the normal thyroid was diminished ( Fig. 2D ). This result led us to the diagnosis of AFTN. The patient was treated temporarily using

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Jean Marc Mizzi, Christopher Rizzo, and Stephen Fava

-converting enzyme inhibitors, angiotensin 2 receptor blockers and aldosterone antagonists were being administered and she was not taking potassium supplementation or herbal medications. Clinical examination revealed reduced power in both her lower limbs and a

Open access

Shuhei Baba, Arina Miyoshi, Shinji Obara, Hiroaki Usubuchi, Satoshi Terae, Masao Sunahara, Takahiro Oshima, Kazuhito Misawa, Takahiro Tsuji, Bunya Takahashi, Yuto Yamazaki, Hironobu Sasano, and Norio Wada

hypertension in WS varied from 5 to 70% in different series ( 4 , 5 , 6 ), and there is a lifetime risk of developing arterial hypertension of 50% ( 5 ). The mean age at diagnosis of hypertension varied widely in the literature, from 4.7 to 38.8 years ( 4

Open access

Chi-Hong Ng, Wing-Sun Chow, Karen Siu-Ling Lam, and Chi-Ho Lee

knowledge, this is the first TSH-producing pituitary macroadenoma diagnosed during pregnancy. Here we discuss the potential issues in the diagnosis and management of this unusual cause of thyrotoxicosis during pregnancy, including those encountered in women

Open access

Samson O Oyibo, Olivia S Green, Nabeel M Laliwala, and Satyanarayana V Sagi

published report of diagnostic confusion between central hypothyroidism and subclinical hypothyroidism because of a slightly raised serum TSH and low-normal serum FT4 ( 8 ). This resulted in a diagnosis of subclinical hypothyroidism. However, before starting