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Serena Khoo, Greta Lyons, Andrew Solomon, Susan Oddy, David Halsall, Krishna Chatterjee and Carla Moran

postpartum thyroiditis ( 9 ). Here we describe a complex case of Hashimoto’s thyroiditis evolving to Graves’ disease with discordant thyroid function, eventually resulting in diagnosis of coexistent FDH, highlighting challenges in diagnosis and management

Open access

Angelo Paci, Ségolène Hescot, Atmane Seck, Christel Jublanc, Lionel Mercier, Delphine Vezzosi, Delphine Drui, Marcus Quinkler, Martin Fassnacht, Eric Bruckert, Marc Lombès, Sophie Leboulleux, Sophie Broutin and Eric Baudin

Background Monitoring plasma mitotane levels is recommended in the follow-up of patients with unresectable adrenocortical carcinoma (ACC) to look for a therapeutic window of 14–20mg/L to optimize benefit over risk and avoid toxicities ( 1

Open access

Ramesh Srinivasan, Stephen Ball, Martin Ward-Platt, David Bourn, Ciaron McAnulty and Tim Cheetham

possibility of inter-current infection but the diagnosis was revised to include one of water intoxication and the DDAVP was stopped. In light of the fact that the biochemistry at the time of DDAVP initiation had not been diagnostic of CDI, it was felt

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Marta Araujo Castro, Ainhoa Abad López, Luz Martín Fragueiro and Nuria Palacios García

loss of staining for parafibromin, a product of the HRPT2 gene (involved in the pathogenesis of PC) has a sensitivity of 67–96% and a specificity of 99% for the diagnosis of PC. As a result, a negative staining is practically diagnostic of PC and a

Open access

Eva Krčálová, Jiří Horáček, Lubomír Kudlej, Viera Rousková, Blanka Michlová, Irena Vyhnánková, Jiří Doležal, Jaroslav Malý and Pavel Žák

in the lower part of the right lobe. In addition, several small cysts (up to 5mm) in the upper part of the right lobe were described. The appearance of the left lobe was unremarkable and lymphadenopathy was not present. Static thyroid gland

Open access

Noman Ahmad, Abdulmonem Mohammed Almutawa, Mohamed Ziyad Abubacker, Hossam Ahmed Elzeftawy and Osama Abdullah Bawazir

express the symptoms of hypoglycemia like adults. A diagnosis of insulinoma is usually delayed in adults and in children due to the vague symptoms. The median interval between the onset of symptoms and diagnosis of an insulinoma is less than 18 months in

Open access

Alicia R Jones, Alan McNeil, Christopher Yates, Bala Krishnamurthy and Peter S Hamblin

.2 mm (AP, trans, SI), (C) pre- and (D) post-contrast sagittal MRI brain 6 months after diagnosis, showing reduction in size of the pituitary stalk, now measuring 4.4 × 4.9 × 5.5 mm. Table 1 Anterior pituitary function results

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Maria Cabrer, Guillermo Serra, María Soledad Gogorza and Vicente Pereg

deficiency, hypocalcemia due to PH, learning difficulties and psychiatric disorders ( 3 ). It is usually diagnosed in newborns or children, but diagnosis can be delayed to adulthood due to variability in type and severity of clinical manifestations. Up to

Open access

Marianne Geilswijk, Lise Lotte Andersen, Morten Frost, Klaus Brusgaard, Henning Beck-Nielsen, Anja Lisbeth Frederiksen and Dorte Møller Jensen

-headedness, headache and hunger, especially during exercise and when trying to lose weight. In 2004, at the time of diagnosis, pre-prandial blood glucose ranged 1.9–2.7 mmol/L, and during oral glucose tolerance test, the blood glucose level was 1.6 mmol/L after 3.5 h

Open access

Kursad Unluhizarci, Hulya Akgun, Bahadır Oz, Zuleyha Karaca, Fatih Tanriverdi and Fahrettin Kelestimur

patient underwent total thyroidectomy for the possible diagnosis of MTC. Histopathologic diagnosis was ‘papillary thyroid carcinoma, follicular variant, 17 and 10 mm in sizes’, as shown in Fig. 1B . Both patients gave their informed consent for the