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Joseph A Chorny, John J Orrego and José Manuel Cameselle-Teijeiro

a radiation oncologist and the consensus was to defer surgery and to treat the cancer as a pulmonary small cell carcinoma utilizing aggressive chemotherapy with 4 cycles of cisplatin and etoposide (VP16), followed by consolidative radiation therapy

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Saurabh Uppal, James Blackburn, Mohammed Didi, Rajeev Shukla, James Hayden and Senthil Senniappan

. Noting the poor initial response, post-operative chemotherapy was escalated to include cycles of cyclophosphamide with doxorubicin and carboplatin with etoposide. He underwent radiotherapy with seven fractions (1.5 Gy per fraction) at a total dose of 10

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Impana Shetty, Sarah Fuller, Margarita Raygada, Maria J Merino, B J Thomas, Brigitte C Widemann, Karlyne M Reilly, Karel Pacak and Jaydira Del Rivero

metastatic ACC or as treatment in cases in which the tumor is unresectable. For more advanced cases, a combination of mitotane with etoposide, doxorubicin, and cisplatin (EDP) is given as standard treatment. Several clinical trials are currently assessing the

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Philip D Oddie, Benjamin B Albert, Paul L Hofman, Craig Jefferies, Stephen Laughton and Philippa J Carter

of oral mitotane and intravenous cytotoxic drugs (cisplatin, etoposide and doxorubicin) as per the ARAR0332 protocol [ https://www.childrensoncologygroup.org/index.php/arar0332 -accessed 29/01/18]. As mitotane is known to cause adrenal insufficiency

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Angelo Paci, Ségolène Hescot, Atmane Seck, Christel Jublanc, Lionel Mercier, Delphine Vezzosi, Delphine Drui, Marcus Quinkler, Martin Fassnacht, Eric Bruckert, Marc Lombès, Sophie Leboulleux, Sophie Broutin and Eric Baudin

performed using Unicel DXC Beckman Coulter Automate (Marseille, France). EP, etoposide-platin; F, fluorouracil; G, gemcitabine; PD, progressive disease; SD, stable disease. Investigation Influence of HCH and HTG on plasma o,p′ -DDD and o

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Tejhmal Rehman, Ali Hameed, Nigel Beharry, J Du Parcq and Gul Bano

, methotrexate, bleomycin, actinomycin, cyclophosphamide and etoposide) followed by TP/TE (paclitaxel/cisplatin alternating with paclitaxel/etoposide). He then had surgery to remove primary and pulmonary metastasis. Histology showed only dead tissue and no active

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S Solomou, R Khan, D Propper, D Berney and M Druce

progression within the liver, the patient agreed to commence chemotherapy in December 2011. Cisplatin and etoposide therapy was commenced on the basis of tumour histopathology. The symptoms of hypoglycaemia remained well controlled and no amendments to the

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Asma Deeb, Hana Al Suwaidi, Salima Attia and Ahlam Al Ameri

tumor resection and six cycles of bleomycin, etoposide, cisplatinum chemotherapy. Remission was achieved and serum fetoprotein reduced from 12 714 to 5 mU/l. She was commenced on prednisolone treatment (2 mg am, 4 mg pm). Puberty was induced with 5 μg

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Carine Ghassan Richa, Khadija Jamal Saad, Georges Habib Halabi, Elie Mekhael Gharios, Fadi Louis Nasr and Marie Tanios Merheb

. Case 3 Chemotherapy with carboplatin and etoposide for stage four neuroendocrine tumors was initiated. Everolimus of 10 mg/day and sandostatin 30 mg every one month were also given thereafter. Outcome and follow-up Case 1 She had

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Katia Regina Marchetti, Maria Adelaide Albergaria Pereira, Arnaldo Lichtenstein and Edison Ferreira Paiva

included cisplatin, etoposide, doxorubicin, and mitotane, whereas the second cycle involved cisplatin; no response to either regimen was observed. After 3 months, the patient’s condition worsened and progressed to death. Outcome and follow-up No