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Hiromi Himuro, Takashi Sugiyama, Hidekazu Nishigori, Masatoshi Saito, Satoru Nagase, Junichi Sugawara, and Nobuo Yaegashi

pregnant naturally, she received prenatal care in a private clinic. Her random plasma glucose level was 140 mg/dl at 8 weeks of gestation, but a 75-g oral glucose tolerance test (75-g OGTT) at 11 weeks showed that her glucose tolerance was normal. At 28

Open access

Chih-Ting Su and Yi-Chun Lin

serum concentrations of glucose and total insulin, an oral glucose tolerance test was performed. After a 75 g glucose load, total insulin level increased markedly at 30 min, but it was kept in high level greater than 80 IU/mL. At the time point of 5 h

Open access

Aoife Garrahy, Matilde Bettina Mijares Zamuner, and Maria M Byrne

gestational diabetes at 19 weeks during her third pregnancy, in 1997. A 100 g oral glucose tolerance test showed time 0 blood glucose 6.1 mmol/L, 1 h 11.1 mmol/L, 2 h 8.3 mmol/L and 3 h 7.8 mmol/L. She had two previous large babies (4.5 kg, 42 weeks gestation

Open access

Nikolaos Kyriakakis, Jacqueline Trouillas, Mary N Dang, Julie Lynch, Paul Belchetz, Márta Korbonits, and Robert D Murray

the size of his hands and feet for a period of 4 years prior to diagnosis. Investigation The patient was diagnosed with acromegaly based on an elevated basal GH level of 181 IU/L, which failed to suppress during an oral glucose tolerance test

Open access

Ramez Ibrahim, Atul Kalhan, Alistair Lammie, Christine Kotonya, Ravindra Nannapanenni, and Aled Rees

response to 250 μg of Synacthen was normal (baseline, 196 nmol/l and 30 min, 673 nmol/l). A glucose tolerance test confirmed failure to suppress serum GH levels (nadir, 60.6 μg/l). Magnetic resonance imaging (MRI) of the pituitary revealed a pituitary

Open access

Shinichiro Teramoto, Yuichi Tange, Hisato Ishii, Hiromasa Goto, Ikuko Ogino, and Hajime Arai

.010–3.607 ng/mL) within the normal range, but elevated insulin-like growth factor 1 (IGF-1) level (381 ng/mL; normal: 61–183 ng/mL). A 75 g oral glucose tolerance test (OGTT) achieved inadequate suppression of nadir GH level (3.190 ng/mL). Acromegaly due to GH

Open access

W K M G Amarawardena, K D Liyanarachchi, J D C Newell-Price, R J M Ross, D Iacovazzo, and M Debono

, hypercalcaemia or renal stones. Examination revealed typical features of acromegaly. Her blood pressure and visual fields were normal. Investigations The oral glucose tolerance test (OGTT) was performed to confirm the diagnosis of acromegaly (nadir GH

Open access

Athanasios Fountas, Shu Teng Chai, John Ayuk, Neil Gittoes, Swarupsinh Chavda, and Niki Karavitaki

glucose tolerance test (nadir: 1.18 µg/L). Notably, when manifestations of acromegaly were discussed at this stage, enlargement of the hands and development of more coarse facial features over the years were noticed. On further review of the pre

Open access

Marina Yukina, Nurana Nuralieva, Maksim Solovyev, Ekaterina Troshina, and Evgeny Vasilyev

within the reference interval). Investigation A continuous blood glucose monitoring system with a portable device was used to perform provocation tests with a 72-h fast ( Figs 1 and 2 ), mixed food, physical exertion ( 23 ), and an oral glucose

Open access

Nishant Raizada, S H Rahaman, D Kandasamy, and V P Jyotsna

extended oral glucose tolerance test with 75 g glucose was performed, which revealed a paradoxical response, i.e., 0, 1, 2, 3, 4 and 5 h plasma glucose 36, 198, 227, 185, 113 and 39 mg/dl with corresponding serum insulin above 1000 μU/ml each time. He