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J Rajkanna, S Tariq and S O Oyibo

Background Infertility affects 15% of couples, and a male factor is a contributory cause in 50% of cases (1) . Adequate history taking, examination of both partners and hormone testing and semen analysis are required to ascertain the cause

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Xin Feng and Gregory Kline

age 9 years with early masculinizing features and presence of longstanding hyperpigmentation. However, by the end of high school, he recalled being the shortest person in the class. Later in life when presenting with infertility, he was noted to be

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Aimee R Hayes, Anthony J O'Sullivan and Mark A Davies

she became convinced that it was more than her neck causing the problem and an urgent endocrine and neurosurgical review was arranged. Investigations for infertility and an irregular menstrual cycle performed two years previously at another facility

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Nandini Shankara Narayana, Anne-Maree Kean, Lisa Ewans, Thomas Ohnesorg, Katie L Ayers, Geoff Watson, Arthur Vasilaras, Andrew H Sinclair, Stephen M Twigg and David J Handelsman

genitalia, etc.) to early adulthood (delayed puberty, infertility). They can be extremely challenging owing to the associated diagnostic and ethical dilemmas. DSDs are rare and need a systematic approach to establish diagnosis through a multidisciplinary

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Anita Kuriya, David V Morris and Michael H Dahan

A 31-year-old African American G2P2L1 type 2 diabetic (DM2) presented with a 3-year history of secondary infertility and amenorrhea without any headaches. She had been diagnosed with DM2 6 years earlier after being tested for it because of her strong

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Ana Marina Moreira and Poli Mara Spritzer

importance of individualized treatment and follow-up and discussing novel and relevant aspects to the approach of POI, such as infertility, association with the fragile X premutation, and osteoporosis management. Case presentation Case 1 A 26-year

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Usman Javaid, Vikram Lal, Catherine Napier, Alison Burbridge and Richard Quinton

previously, the couple had been investigated for primary infertility and given a diagnosis of dual-factor’ infertility, based upon his severe astheno- and terato-zoospermia (68% immotile; 90% abnormal), despite a reasonable overall count (38–43 × 10 6 /mL

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K Majumdar, M Barnard, S Ramachandra, M Berovic and M Powell

Britain in 1924 (4) , the literature on sellar tuberculomas, unsurprisingly, largely arises from the Indian subcontinent and other developing countries. Our patient presented with a history of headaches, amenorrhoea and infertility and the background of

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Kingsley Okolie, Sumathy Perampalam, Anthony Barker and Christopher J Nolan

KS adults are usually in the low to low-normal range ( 1 , 2 ). Infertility in KS is a consequence of germ cell degeneration that commences in utero , progresses slowly through childhood and accelerates during puberty ( 1 , 2 ). The

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Bronwen E Warner, Carol D Inward and Christine P Burren

two with infertility ( 4 ). The clinical endocrine abnormality in our case was bilateral impalpable testes; two papers identify seven cases of cryptorchidism in Lowe syndrome ( 5 , 6 ), but do not specify whether they were undescended but palpable or