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S M Kandel and J A Cosgriff

sepsis, and she required transfer to the intensive care unit for stabilization. The patient was on a home dose of 30 units per day of glargine insulin and an insulin sliding scale. After admission, her blood glucose became unresponsive to her home dose

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Chih-Ting Su and Yi-Chun Lin

about 40 units. He started to use insulin aspart plus insulin glargine since 4 years ago and latest hemoglobin A1c was 7.6%. Frequent hypoglycemia and syncope events were noted for 1 year. At first, hypoglycemic coma happened about twice annually, but

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Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, and Margareth Afonso Torres

values: 4–6%) over time (months of treatment). Treatment with sitagliptin and vitamin D3 started at 0 month. Point A – interruption of insulin glargine and lispro (patient #1), point B – interruption of insulin glargine (patient #2). All tests were

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Mauro Boronat, Rosa M Sánchez-Hernández, Julia Rodríguez-Cordero, Angelines Jiménez-Ortega, and Francisco J Nóvoa

previous amount of long-acting insulin (glargine in both cases), and therapy was begun with only one initial basal rate. Insulin requirements for preprandial boluses were based on insulin-to-carbohydrate ratio used for each meal during the weeks before pump

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E S Scott, G R Fulcher, and R J Clifton-Bligh

1 He was initially managed with an intravenous insulin infusion, and then transitioned to subcutaneous insulin (twice daily glargine supplemented with meal time aspart) with an altered glycaemic target (8–12 mmol/L) due to fear of hypoglycaemia

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Silvia M Becerra-Bayona, Víctor Alfonso Solarte-David, Claudia L Sossa, Ligia C Mateus, Martha Villamil, Jorge Pereira, and Martha L Arango-Rodríguez

arterial disease Losartan, levothyroxine sodium, atorvastatin, acetylsalicylic acid, metformin, insulin glulisine and insulin glargine 2 Chronic occlusive arterial disease and arterial hypertension Atorvastatin, acetylsalicylic acid, Losartan

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Shivani Patel, Venessa Chin, and Jerry R Greenfield

follow-up Blood glucose levels were well controlled on basal bolus insulin. Her hyperglycaemia-associated symptoms had significantly improved. She required 20 units of glargine insulin (Lantus) and 1 unit of insulin aspart (NovoRapid) for every 10 g of

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Joseph Cerasuolo and Anthony Izzo

a total of 5 L normal saline. Over the next 12 h, his venous blood glucose had decreased to 468 mg/dL, and he was started on a basal bolus insulin regimen with 20 units of insulin glargine and 6 units of nutritional insulin lispro. The patient was

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Michelle Maher, Mohammed Faraz Rafey, Helena Griffin, Katie Cunningham, and Francis M Finucane

-controlled hypertension and dyslipidaemia and stable non-alcoholic steatohepatitis. He was taking a basal bolus insulin regime of insulin aspart 20, 18 and 22 units with meals and insulin glargine 40 units nocte, a total dose of 100 insulin units per day. He was also

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Swapna Talluri, Raghu Charumathi, Muhammad Khan, and Kerri Kissell

hyperosmolar hyperglycemia. His physical examination was unremarkable. His management included intrave­nous fluid resuscitation and intravenous regular insulin (0.1 U/kg) followed by subcutaneous glargine insulin (0.25 U/kg). He was observed overnight and was