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R Bou Khalil, M Abou Salbi, S Sissi, N El Kara, E Azar, M Khoury, G Abdallah, J Hreiki and S Farhat

Background One of the frequently used medications for hyperthyroidism is methimazole. Musculoskeletal complaints are common in thyroid disorders and are also described as side effects to anti-thyroid drugs. Myositis is not a classical feature

Open access

Fernando Gomez-Peralta, Pablo Velasco-Martínez, Cristina Abreu, María Cepeda and Marta Fernández-Puente

focus on the most widely used drugs, the rate of liver dysfunction, including mild elevation of transaminase, rise by 15% ( 1 , 2 ). These common ATDs are methimazole (MMI) and propylthiouracil (PTU). Despite their relatively safe profiles, both can

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Ji Wei Yang and Jacques How

/L respectively, while anti-TSH receptor antibody titers were negative. Despite these findings, the patient’s primary physician prescribed methimazole 10 mg PO TID on 4 June 2015. A thyroid ultrasound performed on 8 June 2015 showed a normal-sized, mildly

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Christine Yu, Inder J Chopra and Edward Ha

. Figure 1 Thyroid function tests throughout the patient's course indicating a dramatic decline in free T 3 and free T 4 immediately after therapy with iopanoic acid and methimazole. Please note day 0 represents the day of admission

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Yuri Tanaka, Taisuke Uchida, Hideki Yamaguchi, Yohei Kudo, Tadato Yonekawa and Masamitsu Nakazato

, hyperthyroidism, and cardiomegaly on chest x-ray. He had been prescribed antihypertensives for years. He had no history of heavy drinking, blood transfusion, or drug abuse. Blood tests revealed Graves’ disease. Methimazole, inorganic iodide, hydrocortisone, and a

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Ismael Capel, Elisabet Tasa-Vinyals, Albert Cano-Palomares, Irene Bergés-Raso, Lara Albert, Mercedes Rigla and Assumpta Caixàs

drug was suspended. Treatment She was empirically treated with antithyroidal drugs (methimazole 10 mg q. 8 h), which proved ineffective to control thyroid function: thyrotropin (TSH): <0.014 µU/mL, free thyroxine (FT 4 ): 7.55 ng/dL and free

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Luísa Correia Martins, Ana Rita Coutinho, Mónica Jerónimo, Joana Serra Caetano, Rita Cardoso, Isabel Dinis and Alice Mirante

) – – 0.37 0.18 – – 0.73 0.73 0.73 0.73 0.73 0.37 Methimazole (mg/kg per day) – – – – – – – 0.15 0.20 0.20 0.20 0.23 * Scintigraphic findings of homogeneously increased iodine uptake, suggestive

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Eva Krčálová, Jiří Horáček, Lubomír Kudlej, Viera Rousková, Blanka Michlová, Irena Vyhnánková, Jiří Doležal, Jaroslav Malý and Pavel Žák

, laboratory tests on routine screening revealed hyperthyroidism: thyrotrophin (TSH) 0.065mIU/L, free thyroxine (fT4) 16.67pmol/L, and free triiodothyronine (fT3) 9.61pmol/L. Methimazole (30mg/day) was administered and the patient was referred to an

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Philip C Johnston, Amir H Hamrahian, Richard A Prayson, Laurence Kennedy and Robert J Weil

cosyntropin. Treatment In the context of the initial biochemistry indicating a plurihormonal TSH/GH co-secreting pituitary adenoma, pre-operative treatment with methimazole and octreotide was initiated. She proceeded to transsphenoidal

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Alfredo Di Cerbo, Federica Pezzuto and Alessandro Di Cerbo

the presence of a 0.8 cm diameter microadenoma in the right side of the gland causing a moderate leftward shift of the pituitary stalk. Treatment Since the patient refused radioiodine therapy and thyroidectomy, treatment with methimazole was