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Carolina Shalini Singarayar, Foo Siew Hui, Nicholas Cheong and Goay Swee En

thyrotoxic clinically with a heart rate of 100 beats per minute. Other positive physical findings included a systolic murmur over the left sternal edge, rebound tenderness over the right iliac fossa and bilateral pedal oedema. There were no clinical findings

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F Serra, S Duarte, S Abreu, C Marques, J Cassis and M Saraiva

A case of a 68-year-old woman with a previous history of controlled hypertension and sinusitis developed symptoms of progressive hearing loss over the past year. She also complained of leg oedema and started taking furosemide. At that time, the

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Aysenur Ozderya, Sule Temizkan, Kadriye Aydin Tezcan, Feyza Yener Ozturk and Yuksel Altuntas

a retardation in his secondary sex characters; upon palpation, his bilateral testes were atrophic, and he had a micropenis (<7 cm). An extremity examination revealed an oedema and an ulcerative skin lesion on his left leg. His bilateral superficial

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Natassia Rodrigo and Samantha Hocking

afebrile. Neurological examination revealed no focal deficits and reflexes that were globally brisk but not hyper-reflexic. Cranial nerve examination was normal with no visual field defect. She was noted to have pitting oedema bilaterally to the knees and

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S Solomou, R Khan, D Propper, D Berney and M Druce

cured. On examination, he was found to be cachectic, with darkening of his skin and peripheral oedema. Biochemistry revealed hypokalaemia (1.8 mmol/l), hypomagnesaemia (0.51 mmol/l) and hypocalcaemia (1.73 mmol/l). Vitamin D level was 46 nmol

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Elise Flynn, Sara Baqar, Dorothy Liu, Elif I Ekinci, Stephen Farrell, Jeffrey D Zajac, Mario De Luise and Ego Seeman

63-year-old female presented to a regional hospital with peripheral oedema and worsening hypertension on a background of previously well-controlled hypertension. On examination, she was hypertensive, tachycardic, hirsute and had ecchymoses on her

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S F Wan Muhammad Hatta, L Kandaswamy, C Gherman-Ciolac, J Mann and H N Buch

abdominal obesity, supraclavicular and nape of the neck pad of fat, proximal muscle weakness, bruising and thinning of skin, bilateral leg oedema but no striae. Pulse rate was 72 beats/min (bpm), blood pressure 178/96 mmHg, temperature 37°C, weight 76.4 kg

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Michal Barabas, Isabel Huang-Doran, Debbie Pitfield, Hazel Philips, Manoj Goonewardene, Ruth T Casey and Benjamin G Challis

(anterior and posterior views). (E) Gadolinium-enhanced MRI images of the pancreatic and hepatic lesions. On further inquiry, the patient reported profound weight loss, inappetence, reduced exercise tolerance, palpitations and peripheral oedema

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Jose León Mengíbar, Ismael Capel, Teresa Bonfill, Isabel Mazarico, Laia Casamitjana Espuña, Assumpta Caixàs and Mercedes Rigla

, constipation, muscle weakness and weight gain. Physical examination showed puffy face with under-eye oedema and dry skin. Palpation of the neck showed no goitre or cervical pain. Investigation Laboratory analyses showed hyperglycaemia (417 mg/dL) and

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Benjamin G Challis, Nicolai J Wewer Albrechtsen, Vishakha Bansiya, Keith Burling, Peter Barker, Bolette Hartmann, Fiona Gribble, Stephen O'Rahilly, Jens J Holst and Helen L Simpson

glucocorticoid and antifungal preparations. On examination he was tachycardic (120 beats/min), hypotensive (85/60 mmHg) with a BMI of 24 kg/m 2 . He had hepato-splenomegaly, gross generalised oedema and eczematous perineal rash. Investigation Case 1