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Taiba Zornitzki, Hadara Rubinfeld, Lyudmila Lysyy, Tal Schiller, Véronique Raverot, Ilan Shimon, and Hilla Knobler

enlargement of the pituitary gland, without a focal lesion. The patient had acromegalic features with multiple skin tags, coarse facial features and soft tissue swelling of hands and feet. Serum insulin-like growth factor 1 (IGF1) was elevated, 116

Open access

Soham Mukherjee, Anuradha Aggarwal, Ashu Rastogi, Anil Bhansali, Mahesh Prakash, Kim Vaiphei, and Pinaki Dutta

along with marked swelling and hypoechogenicity of muscles without any localized collection. MRI right leg revealed thickening and edema of the skin/subcutaneous tissue with hyperintensity in muscles of all the compartments of the right leg in short tau

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Laura Hamilton Adams and Derick Adams

–190). She was subsequently referred to Endocrinology for abnormal thyroid function tests and thyroid nodules. Upon examination, the patient was noted to have an enlarged jaw, coarse facial features, soft tissue thickening of her face and hands and bony

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Ruth Mangupli, Adrian F Daly, Elvia Cuauro, Paul Camperos, Jaime Krivoy, and Albert Beckers

phalangeal bones with reduction in joint spaces and soft tissue swelling. Figure 5 Lateral radiograph of the cranium showing a normal sella turcica (black arrow) and cranial hyperostosis (white arrow). Treatment Once a diagnosis

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Noor Rafhati Adyani Abdullah, Wong Lok Chin Jason, and Azraai Bahari Nasruddin

of bilateral knee joints with periarticular soft tissue swelling and thickening. Figure 8 Radiograph of tibia/fibula which demonstrated posterior cortical thickening with subperiosteal new bone formation of bilateral fibula

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Shigenori Nakamura, Teruyuki Masuda, and Masatoshi Ishimori

Background Ectopic thyroid tissue is a rare congenital anomaly characterized by the presence of thyroid tissue in regions other than its normal position, usually from the base of the tongue to the final pre-tracheal position. The prevalence of

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Soledad Bell, Gabriela Alejandra Sosa, Ana del Valle Jaen, and María Fabiana Russo Picasso

showed that the thyroid gland had a mass of 144 g and measured 98×95×45 mm (length×width×depth). The section surface of the right lobe showed a soft, pale, greyish-yellow tissue with a cystic area of 20×10 mm. The left lobe showed similar characteristics

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Lara Ulrich, Graham Knee, and Colin Todd

with the presence of a parathyroid adenoma ( Fig. 2 ). An ultrasound scan (US) of the neck showed a slightly centric hypoechoic solid soft tissue mass in the lower pole of the left lobe of the thyroid gland with significant intra-lesional blood flow

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M L Gild, L Heath, J Y Paik, R J Clifton-Bligh, and B G Robinson

to struma ovarii. She was subsequently treated with radioactive iodine (I 131 ). Stimulated thyroglobulin was initially 3010 µg/L. Extensive skeletal and soft tissue metastatic disease were apparent on the post I 131 scan. Stimulated FDG-PET showed

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P Hanson, M Pandit, V Menon, S Roberts, and T M Barber

fatty tissue fragments measuring 53 mm in aggregate. Microscopically, there were small areas of fat necrosis, fibro-hyaline scar tissue, focal foreign body-type giant cells and small amount of foreign materials. Features were in keeping with the clinical