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Paula Condé Lamparelli Elias Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Marcelo Volpon Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo

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Giovana de Gobbi Azevedo Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Helio Machado Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo

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Gabriel Henrique Marques Gonçalves Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Antonio Carlos Santos Department of Radiology, Hematology and Oncology, Ribeirão Preto Medical School, University of São Paulo

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Livia M Mermejo Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Margaret de Castro Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Ayrton C Moreira Department of Internal Medicine, Division of Endocrinology, Ribeirão Preto Medical School, University of São Paulo

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Background Transsphenoidal surgery (TSS) is the treatment of choice for pituitary adenomas, with the exception of prolactinomas, which are primarily treated with dopamine agonists. In recent years, TSS has undergone significant technical